Organ System and ABVP Core Examination Review Module C : Study Questions: Part 1
 

Autoimmune Skin Disease:

What are some common self-antigens that have been identified to cause autoimmune skin disease?

What are the body's normal mechanisms to protect these self-antigens from been recognized by the immune system?

What are some triggers that can lead to the recognition of self-antigens and subsequent autoimmune skin disease?

In the epidermis, where are the specific self-antigens located?

How does the location of the self-antigens (level within the epidermis) affect the animals clinical presentation?

Based on the location of the self-antigens that are been attacked in Pemphigus foliaceous compared to Bullous pemphigoid, how would a dog present clinically with each of these diseases?

What are the essential diagnostic tests needed to diagnose a specific autoimmune skin disease?

How useful is immunofluorescence compared to routine histopathology?

Where do you send your skin biopsies? Where should you send your skin biopsies?

What do all of the treatments for autoimmune skin disease having common? What is the generally mechanism of action?